Table 3.

Summary statistics of FOI phases 1-3 and PMV at baseline, w6, w12, w24 and w52

	N	Median (min-max, IQR)	p-value
Phase 1
Baseline	28	1.5 (0–16, 9.25)
w6	27	1.0 (0–12, 3.00)	0.069
w12	28	0.5 (0–46, 3.00)	0.171
w24	27	0.0 (0–10, 3.00)	0.004
w52	18	0.0 (0–13, 1.75)	0.091
Phase 2
Baseline	28	19.5 (0–36, 14.50)
w6	27	19.0 (0–43, 13.50)	0.451
w12	28	19.0 (0–50, 13.25)	0.071
w24	27	15.0 (1–48, 15.50)	0.310
w52	18	19.0 (0–35, 12–75)	0.256
Phase 3
Baseline	28	1.0 (0–20, 3.75)
w6	27	2.0 (0.22, 3.50)	0.501
w12	28	2.5 (0–32, 6.25)	0.089
w24	27	1.0 (0–17, 3.00)	0.191
w52	18	0.5 (0–12, 2.00)	0.959
PMV
Baseline	28	5.0 (0–27, 7.00)
w6	27	8.0 (0–25, 7.00)	0.018
w12	28	5.5 (0–36, 9.25)	0.472
w24	27	7.0 (0–23, 8.50)	0.204
w52	18	5.5 (0–23, 5.75)	0.717

FOI fluorescence optical imaging, PMV PrimaVistaMode, IQR interquartile range; significance level of p < 0.05