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. 2022 May 21;22:202. doi: 10.1186/s12890-022-01991-3

Table 3.

Multivariable logistic regression analysis in 165 NTM-PD patients whose serum E2 and 25OHD were measured

Characteristics Osteopenia Osteoporosis
aOR 95% CI P value aOR 95% CI P value
Age, years 1.12 1.05–1.19  < 0.001
Lower BMI, 1 kg/m2 decrease 1.26 1.02–1.57 0.032
Chronic PA infection 3.49 0.61–19.9 0.159
Lower FEV1%predicted, 1% decrease 1.04 1.01–1.07 0.008
Low E2 (< 10 pg/mL) 4.54 1.97–10.5  < 0.001 3.29 1.01–10.7 0.048
Lower 25OHD, 1 ng/mL decrease 1.12 1.03–1.23 0.011

Abbreviations 25OHD 25-hydroxyvitamin D, aOR Adjusted odds ratio, BMI Body mass index, CI Confidence interval, E2 Estradiol, FEV1 Forced expiratory volume in 1 s, NTM-PD Nontuberculous mycobacterial pulmonary disease, PA P. aeruginosa