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. 2022 May 20;22:566. doi: 10.1186/s12885-022-09635-9

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 8 — Stool from BBR treated mice decreased the expression of pro-inflammatory genes infiltration in AOM/DSS mice. A Significant downregulation in the expression of 26 transcripts involved in inflammatory response by RNA-Sequencing after gavage of BBR treated stool to an AOM mouse model. B A systematic diagram showing major inflammatory pathways implicated by down-regulated genes identified by RNA-Sequencing. C qRT-PCR was performed to verify the changes in expression of genes including Cxcl9, IL-1b, and TNF-α. D Western bolt was performed to confirm the changes in expression of genes including IL-1b, TNF-α and NF-κB (*P < 0.05)