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. 2022 May 21;22:427. doi: 10.1186/s12884-022-04737-5

Table 4.

Sensitivity analysis after excluding GDM patients

Quartiles of energy-adjusted carotenoid intakes (OR, 95% CI) Ptrend a Per one-SD increase b
Q1 Q2 Q3 Q4
Total carotenoids
 Crude 1.0 0.75 (0.51, 1.09) 0.61 (0.41, 0.90)* 0.49 (0.32, 0.75)** 0.001 0.71 (0.60, 0.84)**
 Adjusted model 1.0 0.57 (0.31, 1.03) 0.47 (0.24, 0.90)* 0.36 (0.18, 0.69)** 0.002 0.65 (0.51, 0.84)**
α-carotene
 Crude 1.0 1.09 (0.74, 1.60) 0.93 (0.63, 1.37) 0.71 (0.46, 1.09) 0.06 0.91 (0.79, 1.05)
 Adjusted model 1.0 0.89 (0.49, 1.59) 0.87 (0.47, 1.62) 0.67 (0.35, 1.30) 0.24 0.94 (0.77, 1.15)
β-carotene
 Crude 1.0 0.72 (0.49, 1.06) 0.63 (0.42, 0.94)* 0.55 (0.36, 0.83)* 0.004 0.78 (0.67, 0.91)*
 Adjusted model 1.0 0.61 (0.33, 1.11) 0.37 (0.19, 0.71)* 0.36 (0.18, 0.70)* 0.001 0.76 (0.61, 0.95)*
β-cryptoxanthin
 Crude 1.0 0.92 (0.63, 1.34) 0.93 (0.61, 1.41) 0.75 (0.49, 1.14) 0.18 0.73 (0.59, 0.91)*
 Adjusted model 1.0 0.97 (0.54,1.74) 0.79 (0.41, 1.54) 0.49 (0.26, 0.94)* 0.02 0.68 (0.48, 0.98)*
Lycopene
 Crude 1.0 1.01 (0.68, 1.51) 0.81 (0.54, 1.21) 0.59 (0.39, 0.90)* 0.006 0.69 (0.57, 0.84)**
 Adjusted model 1.0 0.69 (0.38, 1.25) 0.58 (0.30, 1.10) 0.61 (0.32, 1.14) 0.14 0.70 (0.53, 0.93)*
Lut-zea
 Crude 1.0 0.81 (0.56, 1.18) 0.62 (0.40, 0.94)* 0.59 (0.39, 0.91)* 0.01 0.82 (0.69, 0.96)*
 Adjusted model 1.0 0.59 (0.31, 1.10) 0.49 (0.25, 0.95)* 0.35 (0.18, 0.69)* 0.003 0.67 (0.51, 0.87)*

GDM Gestational diabetes mellitus, OR Odds ratio, CI Confidence interval, Q Quartile, SD Standard deviation, Lut-zea Lutein and zeaxanthin

a Tested by entering the median intake of each quartile of carotenoids as a continuous variable into univariate and multivariate logistic regression models. b Performed by standardising the energy-adjusted carotenoid intakes data and entering it into the model.

Adjusted model was adjusted for age (years), gestational age (weeks), pre-pregnancy BMI (kg/m2), gravidity, parity, gestational diabetes mellitus (GDM) status (yes/no), family hypertension history (yes/no), physical activity (MET [h/d]), education and income levels and total energy intake (kcal/d)

*P < 0.05; **P < 0.001.