Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 21;4(3):fcac103. doi: 10.1093/braincomms/fcac103

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022. Published by Oxford University Press on behalf of the Guarantors of Brain.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Established markers proteins segregate according to reproducible patterns across fractions. (A) Marker proteins plotted according to their locations along PC1 and PC2. Supplementary Figure 4 shows a faceted plot of each set of organellar markers alone, to inspect proteins in the crowded central region of the plot. The combination of PCs 1 and 2 shows good separation for cytoskeletal and cytosolic proteins in the lower part of PC2, and mitochondrial and post-synaptic proteins in the top half. (B) PC plot of PCs 2 and 3. PC3 nicely separates post-synaptic and mitochondrial proteins from pre-synaptic and plasma membrane proteins. (C) Box plots show the association of marker proteins from each organelle with the top 4 principal components. PC4 separates the nuclear markers from all other organelles. (D) Line plot of the average proportional distribution profile of the marker set for each organelle.