Table 2.

The top five enriched GO terms for each set of SVM assigned organelles

GO ID	Term	Annotated	Significant	Expected	Classic Fisher’s P-value	SVM fraction
GO:0005829	Cytosol	1490	138	103.45	4.30E−07	Cytoplasm
GO:0072562	Blood microparticle	56	11	3.89	0.0013	Cytoplasm
GO:0120115	Lsm2–8 complex	5	3	0.35	0.003	Cytoplasm
GO:1902560	GMP reductase complex	2	2	0.14	0.0048	Cytoplasm
GO:0008537	Proteasome activator complex	2	2	0.14	0.0048	Cytoplasm
GO:0005622	Intracellular	2682	190	181.58	0.0035	Cytoskeleton
GO:0005829	Cytosol	1490	130	100.88	1.90E−06	Cytoskeleton
GO:0070062	Extracellular exosome	950	82	64.32	0.0038	Cytoskeleton
GO:1904813	Ficolin-1-rich granule lumen	84	14	5.69	0.0012	Cytoskeleton
GO:0031093	Platelet alpha granule lumen	22	6	1.49	0.0027	Cytoskeleton
GO:0016021	Integral component of membrane	586	114	70.04	1.20E−9	ER
GO:0005783	Endoplasmic reticulum	333	73	39.8	4.80E−7	ER
GO:0005789	Endoplasmic reticulum membrane	228	69	27.25	5.80E−14	ER
GO:0000139	Golgi membrane	156	38	18.64	0.00011	ER
GO:0030126	COPI vesicle coat	10	9	1.2	4.10E−8	ER
GO:0016021	Integral component of membrane	586	19	11.94	0.0044	Mitochondria
GO:0005739	Mitochondrion	564	47	11.49	0.0022	Mitochondria
GO:0005743	Mitochondrial inner membrane	196	22	3.99	4.70E−7	Mitochondria
GO:0005759	Mitochondrial matrix	185	21	3.77	1.70E−7	Mitochondria
GO:0005947	Mitochondrial alpha-ketoglutarate dehydr…	5	2	0.1	0.0039	Mitochondria
GO:0005654	Nucleoplasm	603	38	12.29	1.50E−12	Nucleus
GO:0000786	Nucleosome	43	15	0.88	4.50E−6	Nucleus
GO:0000788	Nuclear nucleosome	27	10	0.55	3.60E−11	Nucleus
GO:0005604	Basement membrane	23	11	0.47	5.00E−7	Nucleus
GO:0043260	Laminin-11 complex	3	3	0.06	8.00E−6	Nucleus
GO:0016020	Membrane	1868	72	55.49	4.70E−10	Plasma membrane
GO:0022627	Cytosolic small ribosomal subunit	37	8	1.1	8.40E−6	Plasma membrane
GO:0000784	Nuclear chromosome, telomeric region	33	14	0.98	7.30E−14	Plasma membrane
GO:0000788	Nuclear nucleosome	27	14	0.8	2.10E−15	Plasma membrane
GO:0042788	Polysomal ribosome	23	7	0.68	2.70E−6	Plasma membrane
GO:0005743	Mitochondrial inner membrane	196	15	2.03	5.90E−5	Post-synapse
GO:0005759	Mitochondrial matrix	185	8	1.92	0.0064	Post-synapse
GO:0005747	Mitochondrial respiratory chain complex …	39	5	0.4	3.80E−5	Post-synapse
GO:0031305	Integral component of mitochondrial inne…	17	3	0.18	0.0042	Post-synapse
GO:0098831	Pre-synaptic active zone cytoplasmic comp…	11	2	0.11	0.0054	Post-synapse
GO:0005887	Integral component of plasma membrane	185	9	1.79	0.0014	Pre-synapse
GO:0043025	Neuronal cell body	161	6	1.56	0.0051	Pre-synapse
GO:0035579	Specific granule membrane	31	3	0.3	0.003	Pre-synapse
GO:0017101	Aminoacyl-tRNA synthetase multienzyme co…	12	2	0.12	0.0056	Pre-synapse
GO:0070110	Ciliary neurotrophic factor receptor com…	1	1	0.01	0.0097	Pre-synapse

All terms are significantly enriched (classicFisher <0.05). The table shows proteins annotated (‘Annotated’) in that GO term, compared with proteins present in that organellar set (‘Significant’). For enrichment to be significant, the number of proteins in set will be greater than those expected by chance in a data set of this size (‘Expected’).