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. 2022 May 21;12:42. doi: 10.1186/s13613-022-01015-7

Table 2.

Multivariate logistic regression model of factors associated with the use of any adjunctive measures within 28-day follow-up

Variable OR 95% CI p
Age 0.99 0.98–1.00 0.001
Comorbidity
 Chronic respiratory impairment 0.99 0.79–1.24 0.916
 Congestive heart failure 1.20 0.89–1.62 0.241
 Chronic renal failure 1.01 0.75–1.38 0.927
 Chronic liver failure 0.65 0.41–1.03 0.069
 Immune incompetence 1.27 1.02–1.57 0.030
 Diabetes 1.28 1.03–1.57 0.027
Clinical recognition at baseline 1.66 1.38–2.00  < 0.001
Invasive mechanical ventilation (Ref. No.) 1.86 1.37–2.52  < 0.001
PaO2/FiO2 (for each 10 mmHg) 0.95 0.93–0.96  < 0.001
PIP 1.03 1.02–1.04  < 0.001
PEEP 1.15 1.12–1.19  < 0.001
High-income RW (vs Europe) 0.40 0.32–0.50  < 0.001
Middle-income countries (vs Europe) 0.78 0.62–0.98 0.030

Sample size, n = 2654

BMI body mass index, SOFA Sequential Organ Failure Assessment, PEEP positive end-expiratory pressure, PIP peak inspiratory pressure, RR respiratory rate, RW rest of the world