Table 4.
Interventions variable
| Interventions Variable | N (%) |
|---|---|
| Vaccine challenge at the allergy vaccination unit | 40 (100%) |
| Placebo dose administered | 37 (92.5%) |
| Reaction to placebo | 2 (5%) |
| Pfizer-BioNTech COVID-19 vaccine | 34 (85%) |
| Moderna's COVID-19 vaccine | 6 (15%) |
| Protocol for dose administration for challenge | |
| Single dose 100%a | 16 (40%) |
| Split dose 30% and 70%b | 18 (45%) |
| Vaccine administered using a graded dosing protocolc | 6 (15%) |
| Vaccine challenge outcome | |
| Positive test | 2 (5%) |
| Negative test | 38 (95%) |
Abbreviation: COVID-19, coronavirus disease 2019.
a
Single dose: the whole dose of the vaccine administered at once; example: Pfizer-BioNTech COVID-19 vaccine 0.3 mL.
b
Split dose: 2-step administration of the vaccine, with 30 min observation between the doses; example: Pfizer-BioNTech COVID-19 vaccine 0.1 mL and then 0.2 mL.
c
Graded dosing protocol: administering the vaccine in more than 3 steps with 15 to 20 min observation between the doses.