Table 1.
Characteristics of RC-MIBC cohort versus TMT-MIBC cohort after propensity score matching.
| Characteristics | RC-MIBC cohort | TMT-MIBC cohort | χ 2 | P value | ||
|---|---|---|---|---|---|---|
| No. | % | No. | % | |||
| All | 891 | 100.0 | 891 | 100.0 | ||
| Demographic and clinicopathological characteristics | ||||||
| Age at MIBC diagnosis | ||||||
| 60-69 | 494 | 55.4 | 477 | 53.5 | 0.654 | 0.419 |
| 70-79 | 397 | 44.6 | 414 | 46.5 | ||
| Median age (years) | 68 | 69 | ||||
| Gender | ||||||
| Men | 635 | 71.3 | 625 | 70.2 | 0.271 | 0.603 |
| Women | 256 | 28.7 | 266 | 29.8 | ||
| Year at diagnosis | ||||||
| 2005-2009 | 383 | 43.0 | 381 | 42.8 | 0.009 | 0.924 |
| 2010-2014 | 508 | 57.0 | 510 | 57.2 | ||
| Highest education achievement | ||||||
| Elementary school | 396 | 44.5 | 411 | 46.1 | 2.082 | 0.353 |
| Secondary school | 372 | 41.7 | 377 | 42.3 | ||
| University and above | 123 | 13.8 | 103 | 11.6 | ||
| Clinical T stage | ||||||
| T2 | 585 | 65.7 | 597 | 66.4 | 3.936 | 0.269 |
| T3a | 195 | 21.9 | 202 | 22.7 | ||
| T3b | 58 | 6.5 | 57 | 6.4 | ||
| T4a | 53 | 5.9 | 35 | 4.5 | ||
| Charlson Comorbidity Index (CCI) | ||||||
| 0 | 548 | 61.5 | 541 | 60.7 | 0.376 | 0.829 |
| 1 | 185 | 20.8 | 182 | 20.4 | ||
| 2 or more | 158 | 17.7 | 168 | 18.9 | ||
| Treatment information | ||||||
| Neoadjuvant chemotherapy, n (%) | ||||||
| Yes | 153 | 17.2 | 36 | 4.0 | 81.022 | <0.001 |
| No | 738 | 82.8 | 855 | 96.0 | ||
| Adjuvant chemotherapy, n (%) | ||||||
| Yes | 296 | 33.2 | 515 | 57.9 | 108.532 | <0.001 |
| No | 595 | 66.8 | 376 | 42.2 | ||
| Radiation dose, n (%) | ||||||
| <60 Gy | 782 | 87.8 | 467 | 52.4 | 265.607 | <0.001 |
| ≥60 Gy | 109 | 12.2 | 424 | 47.6 | ||
| Response to chemoradiation, n (%) | ||||||
| Complete | 613 | 68.8 | 642 | 72.1 | 2.267 | 0.132 |
| Incomplete | 278 | 31.2 | 249 | 27.9 | ||
The propensity score was constructed for each participant according to the following covariates: age, gender, year at diagnosis, education achievement, clinical T stage, and Charlson Comorbidity Index (CCI). RC: radical cystectomy; TMT: bladder-sparing trimodality therapy; MIBC: muscle-invasive bladder cancer.