. 2022 Mar 2;47(6):1664–1678. doi: 10.1007/s11064-022-03559-3

Table 3.

Effect of geraniol treatment on BDNF and ER stress sensors in all the studied groups

Parameters/groups	Group I (control group)	(Group II) (geraniol group)	(Group III) (d-galactose group)	(Group IV) (d-galactose + geraniol group)
BDNF level (pg/mg protein)	9.8 ± 1.51	9.54 ± 0.97	5.61 ± 1.51*^,#	7.8 ± 1.38*^,#^,&
PERK level (pg/mg protein)	99.08 ± 8.27	99.76 ± 10.89	274.61 ± 12.01*^,#	170.4 ± 16.22*^,#,&
IRE1 level (pg/mg protein)	67.03 ± 8.08	66.91 ± 8.24	217.44 ± 15.27*^,#	116.89 ± 13.07*^,#,&
GRP78 level (ng/mg protein)	3.26 ± 0.81	3.28 ± 1.02	14.96 ± 1.75*^,#	7.75 ± 1.91*^,#^,&
CHOP level (ng/mg protein)	1.32 ± 0.22	1.34 ± 0.25	4.09 ± 0.37*^,#	2.39 ± 0.51*^,#^,&

Data were expressed as mean ± standard deviation. (n = 10/group). Statistical analysis was carried out using one-way ANOVA with Tukey's post hoc test, SPSS computer program

BDNF brain derived neurotrophic factor, CHOP C/EBP homologous protein, GRP78 78-kDa glucose-regulated protein, PERK protein kinase RNA-like endoplasmic reticulum kinase, IRE1 inositol requiring enzyme-1

*Mean significant difference vs control group (P < 0.05)

^#Mean significant difference vs geraniol group (P < 0.05)

^&Mean significant difference vs d-galactose group (P < 0.05)