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. Author manuscript; available in PMC: 2023 Aug 1.
Published in final edited form as: Dis Colon Rectum. 2022 Jul 5;65(8):1052–1061. doi: 10.1097/DCR.0000000000002223

Table 7:

SSI Reduction Bundle Elements Associated with the Absence of SSI by Analytic Approach

SSI Reduction Bundle Element Bivariate Analysis Logistic Regression Bundle Element CNA Principal Component CNA
Preoperative (outpatient)
Oral antibiotics X X X X
Mechanical bowel preparation X X X
Chlorhexidine skin cleansing day before surgery X
Chlorhexidine skin cleansing day of surgery X X
Preoperative (inpatient)
Timely initial administration of appropriate intravenous SSI antibiotic prophylaxis X X
Intraoperative (surgery)
Timely intraoperative re-dosing of appropriate SSI antibiotic prophylaxis X X X
First measured temperature on arrival to PACU is ≥36.0°C X X
Intraoperative skin preparation with chlorhexidine and alcohol-based solution(s) X X
Impermeable wound protector utilization for all incisions X X X X
Utilization of a dedicated clean wound closure tray/instruments X X
Gown and glove change for all scrubbed personnel prior to wound closure X X X
Re-draping prior to wound closure X
Sterile occlusive incisional wound dressing placed in operating room X X X
Postoperative (inpatient)
Duration of intravenous antibiotic prophylaxis is less than 24 hours X
Removal of original operating room incisional dressing on postoperative day 2
Daily chlorhexidine incision cleansing after dressing removal until discharge (but not to exceed postoperative day 7)

SSI = Surgical site infection

X = Association with Decreased/Absence of SSI