Figure 3.

Effects of OTUB2 on migration of HCC cells. After transfected OTUB2 or vectors into Huh7 and MHCC-97h cells for 48 h, the cell migration was assessed by (a) wound healing (n = 3) and (b) transwell (n = 3) assays. After transfected sh-OTUB2-1/2 or the NC into Huh7 and MHCC-97h cells for 48 h, the cell migration was detected by (c) wound healing (n = 3) and (d) transwell (n = 3) assays. Scale bar, 100 μm. Quantitative data are presented as mean ± SD of three replicates. *p < 0.05 and **p < 0.01, compared with the NC or vector group.