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Pathways significantly underrepresented with age. (a) Modules significantly underrepresented with age. Each module consists of significantly decreased pathways (top term) with shared proteins. (b) We further investigated module 2 (M2), predominantly consisting of proteins involved in ribosome biogenesis and translation, and module 4 (M4), mainly consisting of proteins related to DNA replication and repair. (c) Remaining modules less represented with older age
