FIGURE 3.

Predicted dQTcF prolongation (final dQTcF model) by active metabolite composite (GSK3529246) plasma concentration and dosing occasion. Filled black circles and vertical black lines represent means and 90% CI for deciles of observed dQTcF. Horizontal purple lines indicate dQTcF changes of 10 milliseconds (dashed) and 20 milliseconds (solid). C_max, maximum plasma concentration; D, day; dQTcF, QT interval prolongation corrected by Fridericia formula and by baseline; q.d., once daily; W, Week