Table 4. The relationship between gastric cancer and multiple tumor markers stratified by age.
| Variable | Age | Gastric cancer (n = 268) | Control (n = 209) | χ2 | OR 95% CI | P |
|---|---|---|---|---|---|---|
| / | ≤54 | 78 | 151 | |||
| / | >54 | 190 | 58 | 87.571 | 6.342 [4.245–9.474] | <0.001 |
| AFP− | ≤54 | 69 | 144 | |||
| >54 | 156 | 55 | ||||
| AFP+ | ≤54 | 9 | 7 | 15.074 | 3.803 [1.862–7.767] | <0.001 |
| >54 | 34 | 6 | ||||
| NSE− | ≤54 | 73 | 141 | |||
| >54 | 168 | 58 | ||||
| NSE+ | ≤54 | 5 | 10 | 4.592 | 2.580 [1.050–6.336] | 0.032 |
| >54 | 22 | 0 | ||||
| FER− | ≤54 | 76 | 141 | |||
| >54 | 176 | 58 | ||||
| FER+ | ≤54 | 2 | 10 | 1.706 | 0.371 [0.079–1.737] | 0.229 |
| >54 | 14 | 0 | 4.529 | 1.330 [1.235–1.431] | 0.045 | |
| CEA− | ≤54 | 67 | 146 | |||
| >54 | 134 | 53 | ||||
| CEA+ | ≤54 | 11 | 5 | 35.449 | 6.633 [3.318–13.261] | <0.001 |
| >54 | 56 | 5 | ||||
| CA125− | ≤54 | 68 | 142 | |||
| >54 | 147 | 57 | ||||
| CA125+ | ≤54 | 10 | 9 | 3.181 | 2.32 [0.901–5.974] | 0.082 |
| >54 | 43 | 1 | 13.309 | 16.673 [2.243–123.91] | <0.001 | |
| CA153− | ≤54 | 75 | 142 | |||
| >54 | 182 | 57 | ||||
| CA153+ | ≤54 | 3 | 9 | 0.129 | 0.852 [0.355–2.046] | 0.719 |
| >54 | 8 | 1 | ||||
| CA199− | ≤54 | 66 | 144 | |||
| >54 | 138 | 55 | ||||
| CA199+ | ≤54 | 12 | 7 | 32.670 | 6.243 [3.117–12.503] | <0.001 |
| >54 | 52 | 3 | ||||
| CA242− | ≤54 | 66 | 144 | |||
| >54 | 137 | 55 | ||||
| CA242+ | ≤54 | 12 | 7 | 33.589 | 6.372 [3.184–12.753] | <0.001 |
| >54 | 53 | 3 |
Note:
OR, odds ratio; CI, confidence interval.