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. 2022 May 19;10:e13380. doi: 10.7717/peerj.13380

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© 2022 Abbasi et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.

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(A) Docked complex of TLR-8 with the chimeric vaccine construct. (B) Docking complex generated via ClusPro server illustrating binding affinity between TLR-8 and vaccine component. The lowest energy of −1,277.5 kcal/mol was achieved for this model (complex 2). (C) Docking complex generated via HDOCK server which predicted the binding energy as −330.04 for protein and ligand.