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. 2022 May 19;10:e13380. doi: 10.7717/peerj.13380

Table 6. Protein sequence of vaccine constructs V1, V2 and V3 along with their antigenicity analysis.

Vaccine construct Composition/order Sequence Antigenicity score (Threshold = 0.4)
V1 Predicted CTL, HTL & BCL epitopes of spike Glycoprotein with β defensin adjuvant GIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRGRKCCRRKKEAAAKKIADYNYKLGGGSKIADYNYKLGGGSKIADYNYKLGGGSKIADYNYKLGGGSKIADYNYKLGGGSKIADYNYKLGGGSKIADYNYKLGGGSKIADYNYKLAAYVKNKCVNFNAAYVKNKCVNFNAAYVKNKCVNFNAAYVKNKCVNFNAAYVKNKCVNFNAAYVKNKCVNFNAAYVKNKCVNFNAAYVKNKCVNFNKKDLCFTNVYKKDLCFTNVYKKDLCFTNVYKKDLCFTNVYKKDLCFTNVYKKDLCFTNVYKKDLCFTNVYKKDLCFTNVY 1.16
V2 Predicted CTL, HTL & BCL epitopes of spike Glycoprotein with L7/L12 ribosomal protein adjuvant MSDINKLAETLVNLKIVEVNDLAKILKEKYGLDPSANLAIPSLPKAEILDKSKEKTSFDLILKGAGSAKLTVVKRIKDLIGLGLKESKDLVDNVPKHLKKGLSKEEAESLKKQLEEVGAEVELKEAAAKKIADYNYKLGGGSKIADYNYKLGGGSKIADYNYKLGGGSKIADYNYKLGGGSKIADYNYKLGGGSKIADYNYKLGGGSKIADYNYKLGGGSKIADYNYKLAAYVKNKCVNFNAAYVKNKCVNFNAAYVKNKCVNFNAAYVKNKCVNFNAAYVKNKCVNFNAAYVKNKCVNFNAAYVKNKCVNFNAAYVKNKCVNFNKKDLCFTNVYKKDLCFTNVYKKDLCFTNVYKKDLCFTNVYKKDLCFTNVYKKDLCFTNVYKKDLCFTNVYKKDLCFTNVY 1.03
V3 Predicted CTL, HTL & BCL epitopes of spike protein with HABA adjuvant MAENPNIDDLPAPLLAALGAADLALATVNDLIANLRERAEETRAETRTRVEERRARLTKFQEDLPEQFIELRDKFTTEELRKAAEGYLEAATNRYNELVERGEAALQRLRSQTAFEDASARAEGYVDQAVELTQEALGTVASQTRAVGERAAKLVGIELEAAAKKIADYNYKLGGGSKIADYNYKLGGGSKIADYNYKLGGGSKIADYNYKLGGGSKIADYNYKLGGGSKIADYNYKLGGGSKIADYNYKLGGGSKIADYNYKLAAYVKNKCVNFNAAYVKNKCVNFNAAYVKNKCVNFNAAYVKNKCVNFNAAYVKNKCVNFNAAYVKNKCVNFNAAYVKNKCVNFNAAYVKNKCVNFNKKDLCFTNVYKKDLCFTNVYKKDLCFTNVYKKDLCFTNVYKKDLCFTNVYKKDLCFTNVYKKDLCFTNVYKKDLCFTNVY 0.98