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. 2021 Jul 29;5(5):e1507. doi: 10.1002/cnr2.1507

TABLE 5.

Prognostic factors for the prognosis in the patients classified by the hENT1 expression by each antibody

Variables Univariate Multivariate
Hazard ratio (95% Confidence interval) p Hazard ratio (95% Confidence interval) p
The patients with 10D7G2Low (n = 79)
Residual tumor status (R1/R0) 1.81 (0.96–3.41) 0.067 1.67 (0.88–3.18) 0.116
Adjuvant agent (GEM/S‐1) 2.44 (1.45–4.12) 0.001 2.39 (1.41–4.06) 0.001
The patients with 10D7G2High (n = 16)
CA19‐9 (>37 U/ml/≤37 U/ml) 4.77 (0.79–28.9) 0.089 4.86 (0.79–29.8) 0.088
Adjuvant agent (GEM/S‐1) 0.94 (0.22–3.94) 0.931 1.17 (0.26–5.37) 0.931
The patients with SP120Low (n = 295)
Residual tumor status (R1/R0) 2.35 (1.63–3.38) <0.001 1.88 (1.30–2.74) 0.001
Primary tumor status (T3‐T4/T1‐2) 2.64 (1.50–4.63) 0.001 2.14 (1.19–3.85) 0.011
Regional lymph node status (N1/N0) 1.83 (1.35–2.48) <0.001 1.50 (1.08–2.07) 0.015
CA19‐9 (>37 U/ml/≤37 U/ml) 1.87 (1.37–2.57) <0.001 1.59 (1.15–2.20) 0.005
Adjuvant agent (GEM/S‐1) 1.73 (1.31–2.28) <0.001 1.84 (1.39–2.44) <0.001
The patients with SP120High (n = 31)
ECOG performance status (1/0) 2.60 (1.08–6.27) 0.033 2.75 (1.03–7.33) 0.044
CA19‐9 (>37 U/ml/≤37 U/ml) 2.81 (1.19–6.64) 0.018 2.47 (0.50–3.35) 0.047
Adjuvant agent (GEM/S‐1) 0.93 (0.40–2.16) 0.872 0.77 (0.30–2.00) 0.592

Abbreviations: GEM, gemcitabine; hENT1, human equilibrative nucleoside transporter‐1.