TABLE 5.
Variables | Univariate | Multivariate | ||
---|---|---|---|---|
Hazard ratio (95% Confidence interval) | p | Hazard ratio (95% Confidence interval) | p | |
The patients with 10D7G2Low (n = 79) | ||||
Residual tumor status (R1/R0) | 1.81 (0.96–3.41) | 0.067 | 1.67 (0.88–3.18) | 0.116 |
Adjuvant agent (GEM/S‐1) | 2.44 (1.45–4.12) | 0.001 | 2.39 (1.41–4.06) | 0.001 |
The patients with 10D7G2High (n = 16) | ||||
CA19‐9 (>37 U/ml/≤37 U/ml) | 4.77 (0.79–28.9) | 0.089 | 4.86 (0.79–29.8) | 0.088 |
Adjuvant agent (GEM/S‐1) | 0.94 (0.22–3.94) | 0.931 | 1.17 (0.26–5.37) | 0.931 |
The patients with SP120Low (n = 295) | ||||
Residual tumor status (R1/R0) | 2.35 (1.63–3.38) | <0.001 | 1.88 (1.30–2.74) | 0.001 |
Primary tumor status (T3‐T4/T1‐2) | 2.64 (1.50–4.63) | 0.001 | 2.14 (1.19–3.85) | 0.011 |
Regional lymph node status (N1/N0) | 1.83 (1.35–2.48) | <0.001 | 1.50 (1.08–2.07) | 0.015 |
CA19‐9 (>37 U/ml/≤37 U/ml) | 1.87 (1.37–2.57) | <0.001 | 1.59 (1.15–2.20) | 0.005 |
Adjuvant agent (GEM/S‐1) | 1.73 (1.31–2.28) | <0.001 | 1.84 (1.39–2.44) | <0.001 |
The patients with SP120High (n = 31) | ||||
ECOG performance status (1/0) | 2.60 (1.08–6.27) | 0.033 | 2.75 (1.03–7.33) | 0.044 |
CA19‐9 (>37 U/ml/≤37 U/ml) | 2.81 (1.19–6.64) | 0.018 | 2.47 (0.50–3.35) | 0.047 |
Adjuvant agent (GEM/S‐1) | 0.93 (0.40–2.16) | 0.872 | 0.77 (0.30–2.00) | 0.592 |
Abbreviations: GEM, gemcitabine; hENT1, human equilibrative nucleoside transporter‐1.