Figure 2.

Change in soluble biomarkers over the first 24 weeks among people with human immunodeficiency virus (HIV) who initiated antiretroviral therapy (ART) immediately vs deferred ART initiation until 24 weeks after HIV diagnosis. Longitudinal analysis with generalized estimating equations was performed with biomarkers obtained at baseline (week 0) and at weeks 1, 2, 4, 8, 12, and 24 after enrollment, using an interaction term for study week and treatment arm, unadjusted for substance use or estimated date of detectable infection. The shaded area displays 95% confidence intervals around the regression line. Interleukins 1α, 2, and 6 are not displayed. Abbreviations: IFN, interferon; IL, interleukin; IP, interferon-γ–inducible protein; MIP, macrophage inflammatory protein; TNF, tumor necrosis factor; VL, viral load.