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. 2022 May 9;13:866318. doi: 10.3389/fphar.2022.866318

TABLE 1.

General characteristics of elderly patients with outpatient prescriptions.

Year 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 Annual Increase Rate (%)
No. of patients 5,201,276 5,411,592 5,713,734 5,974,108 6,235,700 6,474,327 6,693,802 7,046,476 7,357,078 7,722,213 5.39
Sex
 Male 2,099,908 (40.4) 2,201,909 2,345,343 2,473,240 2,599,708 2,717,929 2,825,863 2,997,317 3,148,275 3,326,394 (43.1) 6.49
 Female 3,101,368 (59.6) 3,209,683 3,368,391 3,500,868 3,635,992 3,756,398 3,867,939 4,049,159 4,208,803 4,395,819 (56.9) 4.64
Age
 65–69 years 1,800,317 (34.6) 1,789,202 1,799,905 1,882,353 1,972,321 2,079,577 2,132,322 2,239,501 2,306,639 2,440,720 (31.6) 3.95
 70–74 years 1,498,662 (28.8) 1,570,977 1,707,598 1,735,553 1,734,561 1,722,208 1,715,513 1,727,090 1,814,482 1,904,724 (24.7) 3.01
 75–79 years 1,008,529 (19.4) 1,090,106 1,160,533 1,232,649 1,306,653 1,344,631 1,413,640 1,537,649 1,573,012 1,578,401 (20.4) 6.28
 80–84 years 553,756 (10.6) 593,460 642,702 685,867 743,492 811,064 878,909 937,345 1,003,923 1,072,901 (13.9) 10.42
 ≥85 years 340,012 (6.5) 367,847 402,996 437,686 478,673 516,847 553,418 604,891 659,022 725,467 (9.4) 12.60
Mean ± SD 73.3 ± 6.4 73.5 ± 6.4 73.6 ± 6.5 73.7 ± 6.6 73.8 ± 6.7 73.9 ± 6.7 74.1 ± 6.8 74.1 ± 6.9 74.2 ± 7.0 74.2 ± 7.1
Disease
 Hypertension 2,581,068 (49.6) 2,698,944 2,871,014 3,020,143 3,127,229 3,251,965 3,377,110 3,520,861 3,690,716 3,880,467 (50.3) 5.59
 Cardio-cerebrovascular diseases 708,464 (13.6) 738,118 769,820 794,857 808,563 824,746 842,376 865,736 908,699 965,318 (12.5) 4.03
 Hyperlipidemia 861,160 (16.6) 1,005,204 1,143,690 1,286,479 1,455,729 1,623,152 1,839,357 2,019,675 2,223,874 2,464,689 (31.9) 20.69
 Diabetes mellitus 1,101,025 (21.2) 1,199,610 1,296,502 1,390,443 1,471,894 1,555,136 1,646,875 1,757,277 1,873,910 2,011,237 (26.0) 9.19
 Gastric ulcer/gastroesophageal reflux disease 900,849 (17.3) 921,419 972,808 955,284 938,610 926,121 924,474 919,140 926,743 901,305 (11.7) 0.01
 Chronic renal failure 53,226 (1.0) 66,545 81,899 93,443 101,129 113,049 129,431 144,899 165,262 187,896 (2.4) 28.11
 Liver disease 404,017 (7.8) 429,352 467,627 500,677 511,073 542,900 585,088 622,770 706,072 804,115 (10.4) 11.00
 Respiratory disease 772,877 (14.9) 813,996 924,936 904,180 939,409 957,361 944,269 934,592 1,000,483 978,788 (12.7) 2.96
 Cancer 3,387,661 (7.5) 366,883 407,504 446,303 480,045 515,727 555,593 599,626 652,336 705,116 (9.1) 9.10
 Musculoskeletal disease 2,078,698 (40.0) 2,194,343 2,329,917 2,442,143 2,550,716 2,652,127 2,771,548 2,904,274 3,054,021 3,251,092 (42.1) 6.27
 Dementia 262,711 (5.1) 312,570 370,475 429,201 482,337 542,291 622,885 721,893 833,164 946,865 (12.3) 28.94
 Fracture 361,346 (6.9) 362,549 401,783 447,012 450,389 471,148 488,964 528,840 568,701 600,456 (7.8) 7.35
Healthcare utilization
 Healthcare spending (billion USD) 3.2 3.5 3.8 4.2 4.6 4.9 5.4 6.0 6.9 7.9 16.33
 Prescription spending (billion USD) 2.9 3.1 3.1 3.2 3.4 3.7 4.1 4.5 4.9 5.5 9.73
 Number of visits (day) 28.4 28.9 31.0 31.0 30.9 30.3 30.4 30.0 30.1 30.3 0.74
 Number of medications per day, Mean ± SD (Median) 4.7 ± 2.4 (4.2) 4.6 ± 2.4 (4.1) 4.7 ± 2.5 (4.1) 4.7 ± 2.6 (4.1) 4.7 ± 2.6 (4.2) 4.7 ± 2.6 (4.2) 4.8 ± 2.7 (4.2) 4.8 ± 2.7 (4.2) 4.9 ± 2.8 (4.3) 4.9 ± 2.9 (4.3) 0.47
 Spending per patient (USD) 618.3 645.8 671.7 700 733.3 753.3 800.8 850 936.7 1,029.2 7.38
 Prescription spending per patient (USD) 561.7 579.2 535.0 535.8 549.2 565.8 612.5 635 672.5 710 2.93

SD: standard deviation.