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. 2022 May 9;10:875818. doi: 10.3389/fchem.2022.875818

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Copyright © 2022 Lv, Ma, Wang, Qu, Qiu and Hua.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Schematic illustration for the synthesis process of TPP-DMON@DDP. (B) The mechanism of overcoming DDP resistance by disturbing mitochondrial redox homeostasis and attacking mitochondria.