Table 1.
Radiological differences between Coronavirus Disease-19 (COVID-19) and early-stage lung cancer with GGO features.
| COVID-19 | Early-stage lung cancer | |
|---|---|---|
| Spatial location | ||
| Number | Multiple | Solitary |
| Laterality | Bilateral | Unilateral |
| Location | Peripheral | Peripheral |
| Involved lobes | 2–4 | 1 |
| Involved Segments | 10–12 | 1 |
| Component | Pure GGO and mixed GGO | Pure GGO and mixed GGO |
| Form | Patchy | Oval |
| Radiographic features | Interlobular septal thickening | Lobulation |
| Air bronchogram | Spiculation | |
| Crazy-paving pattern | Notches | |
| Reticular pattern | Vascular convergence | |
| Halo sign | Pleural indentation | |
| Temporal progression | ||
| Progression rate | Rapid | Slow |
| Disease period | 2-6 weeks | VDT of pure GGO: 813 days VDT of mixed GGO: 457 days |
| Changes on CT | GGOs grow and resolve | GGOs grow |
| Lung involvement increases | Increasing or new solid component | |
| Consolidation |
GGO, ground-glass opacity; VDT, volume doubling time.