TABLE 6.

Effects of DOR activation on brain miRNAs in prolonged hypoxia.

miRNA	1 day			5 days			10 days
	Hypoxia	C + DOR	H + DOR	Hypoxia	C + DOR	H + DOR	Hypoxia	C + DOR	H + DOR
miR-29b	↓	↓	–	↓	–	–	–	–	–
miR-324-3p	↓	↓	–	↓	–	–	–	–	–
miR-347	↓	↓	↓	↓	–	↓	–	–	↓
miR-298	↓	↓	–	↓	–	↓	–	–	–
miR-101b	↓	↓	↓	–	–	↓	–	–	–
miR-466b	↓	↓	↓	↓	–	↓	–	–	–
miR-186	–	–	–	↓	↓	↓	–	–	–
miR-20b-5p				–	–	↓
miR-212				–	–	↓
miR-351				–	↑	↓
let-7f							↓	–	–
miR-29a	–	↓	↓				↓	–	–
miR-511				–	↓	–	↓	↓	–
miR-363*	–	↑	↓	–	–	↓	–	↓	–
miR-370	–	–	–	↓	–	↓	–	–	–
miR-21	–	↓	–	–	–	↓	–	↑	↓
miR-31	–	–	↑	↓	–	↓	–	↓	–

↑, up-regulation; ↓, down-regulation; –, no statistical difference; C, normoxic control; H, hypoxia; DOR, DOR activation. Comparisons: hypoxia vs. C; C + DOR vs. C; H + DOR vs. H. Summarized from our published article (Yang et al., 2012).