TABLE 9.

Effects of DOR activation on liver miRNAs in prolonged hypoxia.

miRNA	1 day			5 days			10 days
	Hypoxia	C + DOR	H + DOR	Hypoxia	C + DOR	H + DOR	Hypoxia	C + DOR	H + DOR
miR-7a-5p	↑			–			–
miR-10a-5p	↑			↑			↓
miR-25-3p	↑			↑			–
miR-26b-5p	↑			↑			–
miR-30e-5p	↑	–		↓	–		–	–
miR-34a-5p	↓		↑	↓		↑	↓		↑
miR-34c-5p	↑			↑			↑
miR-107-3p	↑	–		↑	↓		↑	↓
miR-122-5p	↑	↓		↑	↓		–	↓
miR-128a-3p	↑	–		↑	–		↑	–
miR-135b-5p	↑			–			–
miR-142-5p	↑		↑	↓		↑	↓		↑
miR-145-5p	↑		↑	↑		–	–		↑
miR-146a-5p	–	–	↑	↓	↑	↑	↓	↑	↑
miR-181a-5p	↑			–			↓
miR-182	↓	↑		↓	↑		↓	–
miR-184	–	–		–	↓		–	↓
miR-192-5p	↑	↑	↓	↑	↑	↓	↑	↑	↓
miR-204-5p	↑		↑	–		↑	–		↑

↑, up-regulation; ↓, down-regulation; –, no statistical difference; C, normoxic control; H, hypoxia; DOR, DOR activation. Comparisons: hypoxia vs. C; C + DOR vs. C; H + DOR vs. H. Cited from our previous work (Zhi et al., 2017).