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. 2022 May 9;16:869705. doi: 10.3389/fnsys.2022.869705

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Copyright © 2022 McClure, Erkat, Corbo and Polack.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Recording sessions in trained mice. (A) Schematic representation of the recording setup. (B) Potential behavioral outcomes for a trial. (C) Trial time course. Inter Trial interval (I.T.I) after Hit and CR: 3 s; I.T.I after Miss and FA: 12.5 s. (D) Stimuli shown during the unimodal, audiovisual, and tuning blocks in a session starting with visual reward. Water drops indicate stimuli that are rewarded for that block. (E) Mouse licking probability for the different unimodal and audiovisual stimuli. (F) Activity of neurons during the presentation of the visual stimuli of the audiovisual block (auditory reward). The neuronal activity was recorded simultaneously with the licking activity (top trace), the locomotion of the animal as well as the pupil size (bottom traces).