Table 1.
Characteristics of participants in the training cohort and validation cohort.
| Variable | Training Cohort (n = 50) | Validation Cohort (n = 101) | p-value | |||
|---|---|---|---|---|---|---|
| ESCC, n = 23 n (%) | Control, n = 27 n (%) | ESCC, n = 48 n (%) | Control, n = 53 n (%) | |||
| Age (years) Mean ± SD | 62.3 ± 8.6 | 58.1 ± 7.7 | 62.1 ± 8.67 | 59.2 ± 8.1 | p > 0.05 | |
| Gender | Male (%) | 20 (87.0%) | 7 (87.5%) | 43 (89.6%) | 14 (82.4%) | |
| Female (%) | 3 (13.0%) | 1 (12.5%) | 5 (10.4%) | 3 (17.6%) | ||
| p-value | p > 0.05 | |||||
| Smoking Status | ||||||
| Non-smoker (%) | 10 (43.5%) | 5 (62.5%) | 19 (39.6%) | 10 (58.8%) | ||
| Current or former smoker (%) | 13 (56.5%) | 3 (37.5%) | 29 (60.4%) | 6 (35.3%) | ||
| Unknown (%) | 0 (0%) | 0 (0%) | 0 (0%) | 1 (5.9%) | ||
| p-value | p < 0.001 | |||||
| Stage | ||||||
| I (%) | 7 (30.4%) | – | 14 (29.2%) | – | ||
| II (%) | 6 (26.1%) | – | 16 (33.3%) | – | ||
| III (%) | 10 (43.5%) | – | 18 (37.5%) | – | ||
| p-value | p > 0.05 | |||||
Only healthy controls from Cancer Hospital, Chinese Academy of Medical Sciences were statistically analyzed in Table 1 in both the training cohort and validation cohort. ESCC: esophagus squamous cell carcinoma.