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. 2022 May 9;13:886246. doi: 10.3389/fneur.2022.886246

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Copyright © 2022 Chen, Zhang, Ding, Zhang, Tan, Mei, He and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Consistent cluster analysis of gliomas. (A) Consensus clustering matrix with k = 2. (B) Cumulative distribution function (CDF) for consistent clustering at k = 2–9. (C) For k = 2–9, the relative change in the area under the CDF curve. (D) Sample distribution for k = 2–9. (E) Heatmap and clinicopathologic characteristics of the two clusters established by the consensus expression of the m7G RNA methylation regulators (Red for high expression level, green for low expression level). (F) Comparison of Kaplan–Meier OS rates for overall survival (OS) curves in the two clusters (*p < 0.05, ***p < 0.001).