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. 2022 May 20;14:17590914221100706. doi: 10.1177/17590914221100706

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© The Author(s) 2022

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — Outline of neural innervations of OT neurons in the central nervous system. A-C. Magnocellular OT neurons (A), parvocellular OT neurons (B) and their interconnections (C). Note that: Oxytocin (OT, green triangles) neurons in the parvocellular division (smaller triangles) of the paraventricular nucleus (pPVN) likely belong to different functional groups; OT neurons in the supraoptic nucleus (SON) and PVN connect mutually through axon/axon collaterals (dashed blue arrows) or dendrites (red dashed arrows); the downward arrows indicate inhibition evoked by OT activation of GABAergic interneurons. Abbreviations of neural structures: The third ventricle (3rdV), Accessory magnocellular nuclei (AMN), Anterior cingulate cortex (ACC), Amygdala (Amy), Arcuate nucleus (Arc), Anteroventral third ventricle region (AV3 V), Barrington's nucleus (BAR), Bed nuclei of the stria terminalis (BNST), Bulbospinal system (BSS), Caudate putamen (CPu), Dorsal vagal complex (DVC), Hippocampus (Hipp), Hypophyseal portal system (HPS), Inferior colliculus (IC), Insular cortex (InsC), Intermediate lobe of the pituitary (IPit), Lateral hypothalamus area (LHA), Lateral septum (LS), Left auditory cortex (LAC), Locus coeruleus (LC), Mammillary body complex (MB), Median eminence (ME), Medial prefrontal cortex (mPFC), Medial preoptic area (MPOA), Nucleus accumbens (NAc), Nucleus tractus solitarius (NTS), Olfactory bulb (OB), Parabrachial nucleus (PBN), Phrenic motor nucleus (PMN), Periaqueductal gray (PAG), Piriform cortex (Pir), Posterior pituitary (PPit), Raphe nucleus (RN), Spinal dorsal horn (SDH), Spinal ejaculation generator (SEG). Substantia nigra compact part (SNc), Superior cervical ganglion (SCG), Sympathetic excitatory neuron (SEN), Ventromedial hypothalamic nucleus (VMH), Ventral tegmental area (VTA). Neural connections of OT neurons refer to (Knobloch & Grinevich, 2014; Liao et al., 2020; Zhang et al., 2021).