Table 3.
Most prevalent pneumococcal serotypes, macrolide resistance and genes in carriage and IPD.
| Most prevalent serotypes | Susceptibility | erm(B) | mef(A/E) | |||
|---|---|---|---|---|---|---|
| n (%) | N | Resistant | N | Positive | Positive | |
| n (%) | n (%) | n (%) | ||||
| Carriage-1 (N=280)a | ||||||
| 19F | 59 (21.1) | 59 | 30 (50.9) | 30 | 17 (56.7) | 28 (93.3) |
| 6B | 33 (11.8) | 33 | 12 (36.4) | 12 | 10 (83.3) | 2 (16.7) |
| 23F | 24 (8.6) | 24 | 7 (29.2) | 7 | 2 (28.6) | 5 (71.4) |
| 14 | 13 (4.6) | 13 | 0 | – | – | – |
| 19Ad | 9 (3.2) | 9 | 4 (44.4) | 4 | 4 (100.0) | 0 |
| Carriage-2 (N=208)c | ||||||
| 15C | 24 (11.5) | 24 | 9 (37.5) | 9 | 1 (11.1) | 7 (77.8) |
| 19A | 21 (10.1) | 21 | 20 (95.2) | 20 | 15 (75.0) | 11 (55.0) |
| 6C | 21 (10.1) | 21 | 15 (71.4) | 15 | 3 (20.0) | 12 (80.0) |
| 23A | 17 (8.2) | 17 | 16 (94.1) | 16 | 11 (68.8) | 3 (18.8) |
| 15B | 15 (7.2) | 15 | 0 | – | – | – |
| IPD-1 (N=99)a | ||||||
| 14 | 26 (26.3) | 26 | 3 (11.5) | 3 | 3 (100.0) | 2 (66.7) |
| 6B | 20 (20.2) | 20 | 8 (40.0) | 8 | 8 (100.0) | 0 |
| 19F | 11 (11.1) | 11 | 7 (63.6) | 7 | 7 (100.0) | 6 (85.7) |
| 23F | 6 (6.1) | 6 | 1 (16.7) | 1 | 0 | 0 |
| 19Ae | 4 (4.0) | 4 | 3 (75.0) | 3 | 3 (100.0) | 2 (66.7) |
| IPD-2 (N=58)b | ||||||
| 14 | 11 (19.0) | 11 | 3 (27.3) | 3 | 2 (66.7) | 3 (100.0) |
| 19F | 9 (15.6) | 9 | 8 (88.9) | 8 | 8 (100.0) | 8 (100.0) |
| 23F | 6 (10.3) | 6 | 4 (66.7) | 4 | 4 (100.0) | 4 (100.0) |
| 6B | 6 (10.3) | 6 | 3 (50.0) | 3 | 3 (100.0) | 0 |
| 19A | 5 (8.6) | 5 | 1 (25.0) | 1 | 1 (100.0) | 1 (100.0) |
| IPD-3 (N=81)c | ||||||
| 19A | 42 (51.9) | 42 | 41 (97.6) | 41 | 36 (87.8) | 38 (92.7) |
| 24F | 19 (23.5) | 19 | 18 (94.7) | 18 | 15 (83.3) | 0 |
| 16F | 2 (2.5) | 2 | 0 | – | – | – |
| 23B | 2 (2.5) | 2 | 1 (50.0) | 1 | 1 (100.0) | 1 (100.0) |
| 35B | 2 (2.5) | 2 | 0 | – | – | – |
13-valent conjugate vaccine (PCV13) was inserted into the National Immunization Program in 2015.
a
Pre-PCV7 introduction.
b
Post-PCV7 introduction.
c
Post-PCV13 introduction.
d
Serotype 19A was number 9 among the most prevalente serotypes in Carriage-1.
e
Serotype 19A was number 6 among the most prevalente serotypes in IPD-1.