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. 2022 May 9;13:879337. doi: 10.3389/fimmu.2022.879337

Table 3.

ClusterProfile software was used to perform KEGG pathway enrichment analysis on the differential gene set.

KEGGID Description DGEs number pvalue
lgi00790 Folate biosynthesis 10 0.000
lgi03030 DNA replication 10 0.002
lgi01230 Biosynthesis of amino acids 16 0.002
lgi00010 Glycolysis/Gluconeogenesis 13 0.003
lgi00590 Arachidonic acid metabolism 17 0.005
lgi00730 Thiamine metabolism 7 0.008
lgi00970 Aminoacyl-tRNA biosynthesis 11 0.011
lgi00260 Glycine, serine and threonine metabolism 12 0.012
lgi00830 Retinol metabolism 14 0.016
lgi00480 Glutathione metabolism 17 0.023
lgi00520 Amino sugar and nucleotide sugar metabolism 15 0.027
lgi00230 Purine metabolism 20 0.037
lgi00330 Arginine and proline metabolism 11 0.037
lgi00592 alpha-Linolenic acid metabolism 6 0.048
lgi00030 Pentose phosphate pathway 6 0.064
lgi01200 Carbon metabolism 19 0.067
lgi04145 Phagosome 19 0.105
lgi03410 Base excision repair 6 0.105
lgi00051 Fructose and mannose metabolism 6 0.117
lgi00053 Ascorbate and aldarate metabolism 3 0.124
lgi00340 Histidine metabolism 6 0.129
lgi01040 Biosynthesis of unsaturated fatty acids 6 0.129
lgi03420 Nucleotide excision repair 7 0.140
lgi00900 Terpenoid backbone biosynthesis 4 0.158
lgi00360 Phenylalanine metabolism 3 0.172
lgi00860 Porphyrin and chlorophyll metabolism 4 0.177
lgi04122 Sulfur relay system 4 0.177
lgi00500 Starch and sucrose metabolism 7 0.191
lgi00561 Glycerolipid metabolism 8 0.195

KEGGID: KEGG channel number.

Description: The function description corresponding to the KEGG channel number.

pvalue: Significance test p value.

DGEs number: The number of differential genes annotated to the KEGG pathway number.