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. 2021 Dec 15;42(6):952–965. doi: 10.1177/0271678X211067133

Figure 4.

Figure 4.

Neutralization of RAGE on CD4+ T Cells tips the balance of Treg/Th17 Cells in the periphery after MCAO. A-B: Quantitative analysis of CD4+ from the blood and spleen of mice from different groups (Sham, PBS+MCAO, sRAGE+MCAO). C-F:Representative flow cytometric plots and quantitative analysis of CD4+ROR-γ+, and CD25+Foxp3+CD4+ T cells from the blood and spleen of mice from different groups (Sham, PBS + MCAO, sRAGE + MCAO). G-H: Representative flow cytometric plots and quantitative analysis of CD4+ROR-γ+, and CD25+Foxp3+CD4+ T cells from the blood and spleen of mice from different groups (ACC1 fl/fl  + Sham + PBS, ACC1 fl/fl  + MCAO + PBS, ACC1 fl/fl  + MCAO + sRAGE, CD4 cre ACC1 fl/fl  + MCAO + PBS, CD4 cre ACC1 fl/fl  + MCAO + sRAGE). n = 7 per group. Data are expressed as mean ± SD. P > 0.05, *P ≤ 0.01, ***P ≤ 0.001. One‐way ANOVA, Bonferroni post hoc test.