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. Author manuscript; available in PMC: 2022 May 23.
Published in final edited form as: J Med Chem. 2021 Jan 5;64(1):741–767. doi: 10.1021/acs.jmedchem.0c01735

Scheme 3:

Scheme 3:

Erlotinib moiety conjugated either at p- position of the benzyloxy group having a chiral center at position 3(1’)- or at the m-position without a chiral center at position 3(1’) of the conjugate.