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. 2022 May 3;38(4):271–286. doi: 10.1089/jop.2021.0128

Table 6.

Outcomes of Studies: Retinal Inflammation and Neurodegeneration

Study Adherent leukocytes Macrophages Müller cell gliosis Pro-inflammatory cytokines VCAM-1 expression ICAM-1 expression GFAP expression BDNF expression
Feng et al.29               Decreased to 0.52 ± 0.1-fold
He et al.37         Increased (no raw data)   Increased (no raw data)  
Hernández et al.26             Increased (GFAP score 1–3)  
Liao et al.32       Increased (TNF-a, IL-1b, IL-6, IL-18, IL-12) (no raw data)        
Piano et al.39     No changes (no raw data)          
Qiu et al.43 Increased (no raw data)         Increased (no raw data)    
Sergeys et al.31 Increased (2.5-fold) Increased (3.1-fold) Increased (2.7-fold)          
Wang et al.41 Increased (no raw data)         Increased (no raw data) Increased (no raw data)  
Wang et al.42             Increased (no raw data)