Table 2.

Correlation Completion Accuracy

	MSE	chu_time	darmanis	CMD	chu_time	darmanis
	chu			chu
Blind estimate	0.01008	0.00796	0.00804	0.21217	0.15855	0.22897
SAVER	0.01949	0.01850	0.01476	0.44604	0.40991	0.52235
drImpute	0.01181	0.00796	0.01371	0.23595	0.16050	0.33769
scRMD	0.01125	0.00868	0.00879	0.23598	0.17621	0.26170
PRIME	0.03707	0.03508	0.02661	0.47846	0.42137	0.33218
SCENA_average	0.01285	0.01119	0.01313	0.27283	0.21596	0.42946
SCENA_ridge	0.01212	0.00708	0.00513	0.20497	0.12942	0.12474

MSE and CMD between the reference correlation and the estimated correlation derived from various methods. SCENA_ridge has the lowest MSE and CMD among imputation methods in chu_time and darmanis data, and is lower than the baseline (“Downsample”), which is the sample correlation matrix of the downsampled data. All other imputation approaches perform worse than the baseline.

CMD, correlation matrix distance; MSE, mean squared error.