Fig. 1.

Experimental procedure and stimulus presentation for the behavioral and MEG assessment on fear conditioning. A) Overview of the procedure, including a pre-experimental preparation block, two experimental blocks and a break in between. The two experimental blocks were similar but used different CS+/CS- pairs of Gabor patches and different UCS- TYPES (phobia-related (magenta) vs. phobia-unrelated (cyan)). The order of blocks was counterbalanced across all patients. B) Stimulus sequence during the fear conditioning phase in a phobia-related block. The stimuli were presented repeatedly. While the CS- (blue) served as a safety- signal and never predicted the UCS, the CS+ (red) predicted the UCS in 33% of the cases. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)