Fig. 3.

Significant spatiotemporal clusters revealing UCS-independent associations between neural CS+/CS- difference activations and SPQ-reduction (top row) as well as BAT-reduction (bottom row). A and B) Left dorsolateral prefrontal cortex (dlPFC)- SPQ (A) and left dlPFC- BAT (B) clusters revealed significant negative correlations between the neural CS+/CS- difference and the percentual SPQ and BAT reduction of each patient. Both clusters revealed a negative correlation indicating associations of relatively higher ratings for the CS- and better treatment outcomes. The L-dlPFC-SPQ cluster (top row) which extended to occipito-parietal regions appeared at a rather late latency (287–570 ms) while the L-dlPFC- BAT- cluster (bottom row) appeared at early to mid-latencies (153–213 ms). C and D) There were no significant associations of the remission status and neural CS+/CS- differences in the L-dlPFC-SPQ (C) or L- dlPFC-BAT (D) cluster. Error bars and fields around the correlation line display 95% confidence intervals.