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. Author manuscript; available in PMC: 2022 May 23.
Published in final edited form as: Biochem J. 2021 Dec 10;478(23):4137–4149. doi: 10.1042/BCJ20210647

Figure 2: APA synthesis and inhibitory function.

Figure 2:

A. Synthesis scheme. B. Synthesized APA inhibits the enzymatic activity of ODC. Note that ODC in the enzymatic assay has a concentration of 40 nM, therefore APA at concentrations less than 40 nM can only inhibit a fraction of the activity.