Fig. 5.
Optogenetic activation of PVHAVP neurons causes self-grooming over voracious feeding induced by fasting. A Time courses of behaviors of 2 mice expressing SSFO-EYFP in PVHAVP neurons during refeeding after ~ 24 h fasting without or with blue-light illumination (2 s). The stimulation point is shown by a blue arrow and denoted as 0 min in the time course. B–G Time spent in feeding (B) or grooming (C), number of feeding (D) or grooming bouts (E), mean duration of feeding (F) or grooming bouts (G) for 10 min of refeeding after ~ 24 h food deprivation. Values are mean ± SEM; n = 4; *p < 0.05, **p < 0.005, ***p < 0.001 by Welch's t-test