Table 1.
Clinical characteristics of cases and controls
| Cluster (+) (n = 10) | Cluster (−) (n = 25) | P | |
|---|---|---|---|
| Age, years, mean [95% CI] | 63 [54–72] | 59 [53–66] | 0.504 |
| Sex, F: M | 10:0 | 18:7 | 0.084 |
| WFNS grade, n(%) | 0.528 | ||
| 1 | 4 (40) | 10 (40) | |
| 2 | 2 (20) | 9 (36) | |
| 3 | 0 (0) | 1 (4) | |
| 4 | 2 (20) | 4 (16) | |
| 5 | 2 (20) | 1 (4) | |
| Fisher grade, n (%) | >0.999 | ||
| 1 | 0 (0) | 0 (0) | |
| 2 | 1 (10) | 3 (12) | |
| 3 | 9 (90) | 22 (88) | |
| ICH, n (%) | 5 (50) | 6 (24) | 0.227 |
| Aneurysm location, n (%) | 0.481 | ||
| AComA | 2 (20) | 10 (40) | |
| PComA | 2 (20) | 7 (28) | |
| MCA | 5 (50) | 7 (28) | |
| ACA | 1 (10) | 1 (4) | |
| Cilostazol, n (%) | 5 (50) | 14 (56) | >0.999 |
| DCI, n (%) | 7 (70) | 1 (4) | <0.001 |
| Severe vasospasm n (%) | 9 (90) | 12 (48) | 0.028 |
| New infarction n (%) | 6 (60) | 0 (0) | 0.0001 |
| mRS at 3 months, median [IQR] | 3.50 [0.00–4.25] | 0.00 [0.00–2.00] | 0.021 |
| Recording time, h, median [IQR] | 312 [294–323] | 298 [272–330] | 0.477 |
| SD count, median [IQR] | 32.0 [23.5–54.8] | 0 [0.0–0.5] | <0.001 |
| SD/h, median [IQR] | 0.11 [0.08–0.17] | 0.00 [0.00–0.00] | <0.001 |
| ICP spike count, median [IQR] | 32.50 [2.00–49.50] | 2.00 [0.00–9.00] | 0.012 |
| ICP spike/h, median [IQR] | 0.10 [0.01–0.16] | 0.01 [0.00–0.03] | 0.011 |
ACA = anterior cerebral artery; AComA = anterior communicating artery; DCI = delayed cerebral ischaemia; IQR = interquartile range; MCA = middle cerebral artery; mRS = modified Rankin Scale; PComA = posterior communicating artery; WFNS = World Federation of Neurosurgical Society. Statistical testing was performed using t-test (age), Fisher’s exact test (sex, Fisher grade), Chi-square test (WFNS grade, aneurysm location) and Mann-Whitney U-test (recording time, SD count, SD/h, ICP spike count, ICP spike/h).