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Model of stage 2 of saliva secretion. Isotonic saliva secreted by acinar cells is rich in NaCl. As it travels through the ductal system, duct cells reabsorb NaCl via CFTR and ENaC while exporting via both CFTR and Slc26a6. The resulting saliva is hypotonic and near neutral pH. See glossary for abbreviations. Created with BioRender.com, with permission.
