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. 2022 May 23;14:69. doi: 10.1186/s13148-022-01289-5

Table 2.

Positive enriched pathways of GSEA result for placenta transcriptome (top20)

Pathway Size NES P value FDR
Cortisol synthesis and secretion 64 0.50  < 0.001 0.16
Adherens junction 71 0.49  < 0.001 0.097
Notch signaling pathway 59 0.48  < 0.001 0.083
Autophagy 32 0.47  < 0.001 0.085
Growth hormone synthesis, secretion and action 118 0.46  < 0.001 0.087
ERBB signaling pathway 85 0.46  < 0.001 0.075
Snare interactions in vesicular transport 33 0.45 5.52e-3 0.075
Lysine degradation 63 0.43  < 0.001 0.10
Ovarian steroidogenesis 50 0.43  < 0.001 0.093
Insulin secretion 84 0.43  < 0.001 0.089
Alpha-linolenic acid metabolism 24 0.42 0.0175 0.086
GNRH signaling pathway 92 0.41  < 0.001 0.10
Prolactin signaling pathway 69 0.41  < 0.001 0.094
Inositol phosphate metabolism 73 0.41  < 0.001 0.091
Chronic myeloid leukemia 76 0.41  < 0.001 0.087
Aldosterone synthesis and secretion 97 0.41  < 0.001 0.082
Phosphatidylinositol signaling system 96 0.40  < 0.001 0.092
Hedgehog signaling pathway 56 0.40  < 0.001 0.087
Endometrial cancer 58 0.40  < 0.001 0.089
Acute myeloid leukemia 67 0.40  < 0.001 0.086

Size represents the number of genes enriched in the corresponding pathway

NES Normalized enrichment score, FDR False discovery rate