TABLE 1.
Functional enrichment analyses identify genes and pathways that are upregulated or downregulated during indicated liver injury
| Injury type | Term | Fold enrichment | p value | Change |
|---|---|---|---|---|
| Chronic‐ethanol‐binge‐induced liver injury in wild type mice | GO:0055114~oxidation‐reduction process | −3.49554532 | 4.72E‐13 | Down |
| Mmu00830:Retinol metabolism | −5.194388162 | 4.33E‐05 | Down | |
| GO:0019433~triglyceride catabolic process | 11.02560976 | .00531723 | Up | |
| GO:0048661~positive regulation of smooth muscle cell proliferation | 5.088742964 | .00638916 | Up | |
| GO:0050729~positive regulation of inflammatory response | 5.25029036 | .005597808 | Up | |
| mmu04390:Hippo signaling pathway | 2.302091518 | .057852084 | Up | |
| Ethanol/CCl4 cotreatment in the hepatocyte‐specific Yap1 KO | GO:0055114~oxidation‐reduction process | −3.61466496 | 6.78E‐12 | Down |
| Mmu00830:Retinol metabolism | −7.63762278 | 2.47E‐08 | Down | |
| GO:0045766~positive regulation of angiogenesis | 8.160437763 | 1.08E‐09 | Up | |
| GO:0048661~positive regulation of smooth muscle cell proliferation | 7.714163823 | 5.61E‐06 | Up | |
| GO:0016477~cell migration | 3.5541697 | .001 | Up |