Table 11:
Hemolytic prediction of activity for LL-37 human cathelicidin peptide
| Test sequence: | LL-37: LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES | |
|---|---|---|
| Prediction results | ||
| Program used | Predicted result | Notes |
| HemoPred | Hemolytic | |
| HemoPI PROB score | 0.34 (SVM (HemoPI-1) based 0.72 (SVM (HemoPI-2) based) (Hemolytic) 0.88 SVM (HemoPI-3) based) (Hemolytic) |
Note from website: PROB score is the normalized SVM score and ranges between 0 and 1, i.e. 1 very likely to be hemolytic, 0 very unlikely to be hemolytic. |
| HAPPENN PROB score | 0.089 (Not Hemolytic) | Note from website: PROB score is the normalized sigmoid score and ranges between 0 and 1. 0 is predicted to be most likely non-hemolytic, 1 is predicted to be most likely hemolytic. |