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. 2022 May 9;9:819311. doi: 10.3389/fmed.2022.819311

Figure 2.

Figure 2

Overall similarity and differences between samples by PCA and OPLS-DA analysis. (A) PCA score plots of healthy controls (HC), diabetic controls (DC), diabetic kidney disease patients [DKD, i.e., Diabetic nephropathy (DN)]. (B,C) OPLS-DA score and model overview plots of HC, DC, and DKD. (D) 1,000-times permutation test of the model showed its high strong reliability.