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. Author manuscript; available in PMC: 2022 May 23.
Published in final edited form as: J Bone Miner Res. 2020 May 13;35(8):1549–1561. doi: 10.1002/jbmr.4023

Table 1:

μCT of male and female (virgin and lactating) control and TβRIIocy−/− mouse bones.

Male Female Lactation
Control TβRII ocy−/− Control TβRII ocy−/− Control TβRII ocy−/−
Distal Femur
Tb.BV/TV(%) 0.18 ± 0.04 0.30 ± 0.07* 0.08 ± 0.04 0.1 ± 0.05 0.04 ± 0.01a 0.08 ± 0.02b
Tb.N (1/mm) 5.30 ± 1.08 6.11 ± 0.87 2.44 ± 0.72 2.68 ± 1.13 1.76 ± 0.45 2.89 ± 0.84
Tb. Th (mm) 0.03 ± 0.003 0.05 ± 0.01* 0.033 ± 0.01 0.035 ± 0.01 0.022 ± 0.002 a 0.027 ± 0.00a,b,c
Tb. Sp (mm) 0.16 ± 0.05 0.12 ± 0.03* 0.40 ± 0.12 0.42 ± 0.22 0.59 ± 0.2 a 0.35 ± 0.15 b,c
SMI 1.71 ± 0.36 0.52 ± 0.62* 2.83 ± 0.43 2.74 ± 0.66 3.01 ± 0.27 2.48 ± 0.38
Tb. Min (mg HA/cm3) 1065.5 ± 18.9 1098.3 ± 16.3* 1103.85 ± 30.2 1096.5 ± 23.6 1010.5 ± 27.0a 1035.3 ± 40.9c
Midshaft Femur
Ct. BA/TA(%) 0.28 ± 0.03 0.30 ± 0.03 0.28 ± 0.02 0.29 ± 0.02 0.21 ± 0.03a 0.24 ± 0.02a,b,c
Ct. Th(mm) 0.20 ± 0.01 0.22 ± 0.02* 0.19 ± 0.01 0.20 ± 0.01 0.14 ± 0.006a 0.16 ± 0.007c
Ct. SMI 0.16 ± 0.41 2.82 ± 1.42* 0.28 ± 0.14 0.12 ± 0.23 0.22 ± 0.03 0.10 ± 0.18
Ct. Min (mg HA/cm3) 1385.8 ± 14.4 1337.8 ± 18.7* 1362.60 ± 46.6 1332.5 ± 66.4 1330.3 ± 29.1 1319.2 ± 36.5
 
*

p<0.05 significantly different from the male control virgin (Student’s t-test),

a

p<0.05 significantly different from the control virgin,

b

p<0.05 significantly different from the control lactation, and

c

p<0.05 significantly different from the virgin TβRIIocy−/− mice.