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. 2022 May 23;18(5):e1010209. doi: 10.1371/journal.pgen.1010209

Fig 8. Characterization of the variability in ttx-3 and ceh-10 expression using correlation analysis.

Fig 8

(A) Differentiation between intrinsic (uncorrelated) and extrinsic (correlated) sources of noise by tagging one allele of a gene with yfp and the other with mkate2. (B) Correlation between the fluorescence levels (arbitrary units) of ttx-3endo::yfp and ttx-3endo::mkate2 (vba3 / vba6 heterozygote animals, n = 52 neurons analyzed). (C) Correlation between the fluorescence levels of ceh-10endo::yfp and ttx-3endo::mkate2 (vba1; vba6 double homozygote animals, n = 106 neurons analyzed). (D) Correlation between the fluorescence levels of ttx-3endo::yfp and his-72endo::mcherry (vba3; vba5 double homozygote animals, n = 49 neurons analyzed). (E) Correlation between the fluorescence levels of ceh-10endo::yfp and his-72endo::mcherry (vba1; vba5 double homozygote animals, n = 101 neurons analyzed). Each grey dot represents one AIY neuron. r = Spearman’s correlation.