TABLE 1.
Patient characteristics of ever-smokers and never-smokers before and after matching (N = 1548)
| Before matching | After matching | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
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| Characteristic | Never-smokers (n = 172) | Ever-smokers (n = 1376) | Standardized difference, % | Never-smokers (n = 169) | Ever-smokers (n = 165) | Standardized difference, % | ||||
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| n* | No. (%) or 15th/50th/85th percentiles | n* | No. (%) or 15th/50th/85th percentiles | n* | No. (%) or 15th/50th/85th percentiles | n* | No. (%) or 15th/50th/85th percentiles | |||
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| Demographics | ||||||||||
| Age, y | 172 | 53/68/78 | 1376 | 56/68/77 | −7.9 | 169 | 53/69/78 | 165 | 53/68/79 | −2.6 |
| Female sex | 172 | 109 (63) | 1376 | 623 (45) | 37 | 169 | 106 (63) | 165 | 103 (63) | 0.09 |
| Body surface area, m2 | 172 | 1.6/1.9/2.2 | 1376 | 1.7/1.9/2.2 | −28 | 169 | 1.6/1.9/2.2 | 165 | 1.6/1.9/2.2 | −1.4 |
| Body mass index, kg/m2 | 172 | 22/26/32 | 1372 | 22/27/33 | −15 | 169 | 22/26/32 | 165 | 22/26/32 | 0.73 |
| Race | ||||||||||
| Black | 169 | 10 (5.9) | 1323 | 134(10) | −16 | 166 | 9.7 (5.9) | 160 | 18(11) | −19 |
| White | 169 | 142 (84) | 1323 | 1169 (88) | −13 | 166 | 140 (85) | 160 | 139(87) | −6.7 |
| Other | 172 | 10 (5.8) | 1376 | 2(0.15) | 34 | 169 | 8.5 (5.1) | 165 | 1.0 (0.63) | 27 |
| Smoking | ||||||||||
| Pack-years | 172 | 1376 | — | 169 | 165 | — | ||||
| ≤10 | 172 (100) | 100 (7.3) | 169 (100) | 22(13) | ||||||
| 11–20 | 0(0) | 157 (11) | 0(0) | 29 (17) | ||||||
| 21–40 | 0(0) | 437 (32) | 0(0) | 58 (35) | ||||||
| 41–60 | 0(0) | 346 (25) | 0(0) | 31 (19) | ||||||
| ≥61 | 0(0) | 336 (24) | 0(0) | 26(16) | ||||||
| Lung function | ||||||||||
| FEV1, % of predicted | 159 | 73/92/110 | 1291 | 63/81/101 | 54 | 156 | 74/93/108 | 157 | 73/93/111 | −1.1 |
| Lung diffusion test, % of predicted | 121 | 72/89/106 | 999 | 56/74/93 | 80 | 120 | 72/89/106 | 119 | 66/85/112 | 8.8 |
| Comorbidities | ||||||||||
| Hypertension | 166 | 88 (53) | 1346 | 836 (62) | −18 | 163 | 87 (53) | 160 | 87 (55) | −2.2 |
| Steroids | 166 | 8 (4.8) | 1346 | 88 (6.5) | −7.4 | 163 | 8 (4.9) | 160 | 10 (6.3) | −6.1 |
| Coronary artery disease | 166 | 22 (13) | 1346 | 318 (24) | −27 | 163 | 22 (14) | 160 | 22(14) | 0.06 |
| Peripheral arterial disease | 166 | 9 (5.4) | 1346 | 144(11) | −19 | 163 | 8.7 (5.4) | 160 | 9.1 (5.7) | −1.4 |
| Prior cardiothoracic surgery | 166 | 28 (17) | 1345 | 223 (17) | 0.77 | 163 | 28 (17) | 160 | 27 (17) | −0.46 |
| Preoperative chemotherapy | 166 | 29 (17) | 1346 | 164 (12) | 15 | 163 | 28 (17) | 160 | 26 (16) | 2.5 |
| Preoperative radiation | 166 | 26 (16) | 1346 | 172(13) | 8.3 | 163 | 26 (16) | 160 | 26 (16) | −0.82 |
| Pharmacologically treated diabetes | 172 | 21 (12) | 1376 | 252(18) | −17 | 168 | 21 (13) | 165 | 21(13) | −1.6 |
FEV1, Forced expiratory volume in 1 second.
*
Patients with data available.