Table 2.
Comparisons | Number of participants | Number of cases | Crude incident rate per 100,000-person years | Hazard ratio (95% confidence interval) | ||
---|---|---|---|---|---|---|
373,026 | 9185 | 195.3 | Model 1a | Model 2b | Model 3c | |
Categories of TV viewing | ||||||
≥4h/day (reference) | 106,510 | 3501 | 261.8 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
2–3h/day | 191,555 | 4413 | 182.5 | 0.81 (0.78–0.85) | 0.94 (0.89–0.98) | 0.94 (0.90–0.99) |
≤1h/day | 74,961 | 1217 | 133.9 | 0.66 (0.62–0.70) | 0.83 (0.78–0.89) | 0.84 (0.79–0.90) |
Categories of computer use | ||||||
≥4h/day (Reference) | 19,253 | 515 | 213.6 | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) |
2–3h/day | 60,596 | 1719 | 226.9 | 0.92 (0.83–1.02) | 1.01 (0.91–1.11) | 1.00 (0.91–1.10) |
≤1h/day | 293,177 | 6951 | 187.6 | 0.78 (0.71–0.85) | 1.00 (0.92–1.10) | 0.99 (0.91–1.09) |
aModel 1: Adjusted for no confounders
bModel 2: Adjusted for all confounders in Model 1 plus sex, body mass index (weight in kilograms/height in meters squared), smoking status (never, previous, current), employment (unemployed, employed), Townsend Deprivation Index (a numerical deprivation score generated based on employment, car ownership, home ownership and household overcrowding according to postcode of participants’ home address), alcohol consumption (never, previous, currently <3 times/week, currently ≥3 times/week), salt-adding behaviour (never/rarely, sometimes, usually, always), oily fish consumption (never, <once/week, once/week, >once/week), coffee intake (cups/day), fruit and vegetable intake (a composite score generated based on intake of fresh/dried fruit and intake of raw/cooked vegetable ranging from 0 to 4), processed/red meat intake (days/week), hypertension medication use, cholesterol-lowering medication use, glucose-lowering medication use, sleep (≤5, 6, 7, 8 and ≥9h/day) and moderate-to-vigorous physical activity (minutes/day)
cModel 3: Adjusted for all confounders in Model 2 plus the polygenic risk score, genotype array type and first ten principal components of genetic ancestry