Figure 2.
Capsaicin prevents renal tubular cell apoptosis in CA-AKI. (a) Representative immunohistochemistry staining of TUNEL in sections of the kidney from mice in the control, CA-AKI, CA-AKI+vehicle, and CA-AKI+CAP groups. Quantification of TUNEL-positive cells (b) and representative Western blotting bands and protein expression quantification of cleaved caspase-3 (c), Bax (d), and Bcl-2 (e) in the kidney of mice in the control, CA-AKI, CA-AKI+vehicle, and CA-AKI+CAP groups. Data are means ± SEM. N = 8 in each group. ∗∗p < 0.01 vs. Ctrl; ##p < 0.01 vs. CA-AKI.