Fig. 4. Dynamics of the forced oscillator.

Here, we either added (a) 1 × = 214 nM aTc every 4 h (λ = 1.43), or (b) 50 nM TetR every 5 h (λ = 1.48). Once added, the input signals are removed by the dilution with fresh reagent (without input), which results in an exponential decay of the input signal. The oscillator responds by increasing, or decreasing the production of σ²⁸, respectively, and synchronizes to the input period. Colored triangles indicate the time points of input addition.